PT-141 (10 Vials)
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PT-141 (10 Vials)

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For Laboratory Research Only: This listing is intended strictly for qualified researchers conducting laboratory work. Completing a purchase confirms you meet this criteria and will not use the product for personal or human consumption.
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Description

PT-141 (Bremelanotide)

PT-141 (bremelanotide) stands apart from most peptides studied for sexual function because its site of action is the brain, not the vasculature. Where many compounds in this space work by acting on blood vessels, PT-141 instead binds receptors in the hypothalamus and limbic system, the areas of the brain governing motivation, desire, and arousal. That distinction makes it a useful tool for researchers looking at how the central nervous system, rather than peripheral blood flow, drives these responses.

Key research findings

  • Receptor binding in the brain sets off a downstream chemical signalling cascade inside nerve cells, giving researchers a consistent method for engaging and studying the melanocortin system under lab conditions (Molinoff et al., 2003)
  • Pharmacokinetic work in healthy male subjects tracked the compound’s behavior post-administration, showing peak concentration at roughly 30 minutes and clearance within about two hours, data that’s useful for building precise dosing timelines in study protocols (Diamond et al., 2004)
  • In subjects who hadn’t responded to standard vascular-acting compounds, PT-141 still produced measurable effects, evidence that its brain-based mechanism operates independently rather than duplicating existing approaches (Rosen et al., 2004)
  • PT-141 has demonstrated the ability to cross the blood-brain barrier in preclinical studies, a trait most peptides lack, which is precisely what enables its central activity and makes it valuable for research into how brain receptor engagement translates into physiological effects (Molinoff et al., 2003)

For research use only. Not intended for use in humans or animals.

References

Molinoff, P.B., et al. (2003). https://pubmed.ncbi.nlm.nih.gov/12851303/

Diamond, L.E., et al. (2004). https://pubmed.ncbi.nlm.nih.gov/14963471/

Rosen, R.C., et al. (2004). https://pubmed.ncbi.nlm.nih.gov/14999221/

Additional information

Size

10mg/vial
What is a peptide, exactly?

Peptides are short chains of amino acids, smaller than proteins, that function as signalling molecules within biological systems. They're involved in processes such as tissue repair, immune activity, and communication between cells.

What role do peptides play in research?

Peptides are studied for how selectively they bind to receptors and influence specific cellular pathways. That precision makes them a valuable tool in laboratory settings for investigating how biological systems function at a molecular level.

What are my payment options?

Card payment, UK bank transfer, and cryptocurrency (Bitcoin and Ethereum) are all accepted.

How do I store this product correctly?

This product ships lyophilised (freeze-dried) to remain stable throughout transit and storage. Keep it cool, dry, and shielded from direct light before use, refrigerating if holding it longer term. Once reconstituted, refrigerate immediately and handle with standard sterile technique to preserve integrity.

What are your shipping timeframes?

Delivery is UK-only. Orders placed before 2pm on a business day go out same-day; anything later, or placed on a weekend, ships the next business day. Most orders arrive within 48 hours of dispatch, with tracking sent directly to you. Orders over £200 ship free automatically.

What's your policy on returns?

As a research product, this item isn't eligible for standard returns. If it arrives damaged or you received the wrong item, reach out within 48 hours and we'll get it resolved.

How is purity confirmed for this product?

Every batch is independently tested in a laboratory before listing, confirming it meets research-grade purity standards. A Certificate of Analysis is available for this product.

PT-141 (Bremelanotide)

PT-141 (bremelanotide) stands apart from most peptides studied for sexual function because its site of action is the brain, not the vasculature. Where many compounds in this space work by acting on blood vessels, PT-141 instead binds receptors in the hypothalamus and limbic system, the areas of the brain governing motivation, desire, and arousal. That distinction makes it a useful tool for researchers looking at how the central nervous system, rather than peripheral blood flow, drives these responses.

Key research findings

  • Receptor binding in the brain sets off a downstream chemical signalling cascade inside nerve cells, giving researchers a consistent method for engaging and studying the melanocortin system under lab conditions (Molinoff et al., 2003)
  • Pharmacokinetic work in healthy male subjects tracked the compound’s behavior post-administration, showing peak concentration at roughly 30 minutes and clearance within about two hours, data that’s useful for building precise dosing timelines in study protocols (Diamond et al., 2004)
  • In subjects who hadn’t responded to standard vascular-acting compounds, PT-141 still produced measurable effects, evidence that its brain-based mechanism operates independently rather than duplicating existing approaches (Rosen et al., 2004)
  • PT-141 has demonstrated the ability to cross the blood-brain barrier in preclinical studies, a trait most peptides lack, which is precisely what enables its central activity and makes it valuable for research into how brain receptor engagement translates into physiological effects (Molinoff et al., 2003)

For research use only. Not intended for use in humans or animals.

References

Molinoff, P.B., et al. (2003). https://pubmed.ncbi.nlm.nih.gov/12851303/

Diamond, L.E., et al. (2004). https://pubmed.ncbi.nlm.nih.gov/14963471/

Rosen, R.C., et al. (2004). https://pubmed.ncbi.nlm.nih.gov/14999221/

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