GHK-Cu

GHK-Cu

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£42.00

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Kit (10 Vials)
Research Use Only: These products are intended for laboratory research purposes only. By purchasing, you confirm you are a qualified researcher and understand this product is not for personal use.
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Description

GHK-Cu (Copper Peptide)

GHK-Cu is a naturally occurring tripeptide — glycyl-L-histidyl-L-lysine — complexed with copper(II). First isolated from human plasma albumin in 1973, it is found naturally in plasma, saliva, and wound fluid, but its concentrations decline significantly with age. It has since become one of the most extensively studied peptides in tissue repair and regenerative research (Pickart & Margolina, 2018).

Mechanism of Action

  • GHK-Cu works by attracting immune and repair cells to sites of tissue damage, stimulating fibroblasts — the cells responsible for building and maintaining connective tissue — to produce collagen, elastin, and structural proteins that form the scaffolding of healthy tissue (Maquart et al., 1988)
  • It simultaneously regulates enzymes that break down old or damaged tissue while activating inhibitors of those same enzymes, allowing for controlled and balanced tissue remodelling (Pickart & Margolina, 2018)
  • The copper component activates key enzymes involved in antioxidant defence, blood vessel formation, and connective tissue integrity (Errante et al., 2020)

Key Research Findings

  • Collagen synthesis in cultured fibroblasts was shown to increase significantly with GHK-Cu at concentrations as low as 10⁻¹² mol/L, maximising at 10⁻⁹ mol/L — demonstrating potent biological activity at very small amounts (Maquart et al., 1988)
  • Gene expression analysis revealed GHK-Cu modulates a broad range of biological pathways, with documented effects on wound healing genes, antioxidant responses, anti-inflammatory signalling, and DNA repair processes (Pickart & Margolina, 2018)
  • Preclinical wound models demonstrated accelerated healing of diabetic and ischemic wounds, with reduced inflammatory markers and increased collagen deposition compared to controls (Gorski et al., 2020)

For research use only. Not intended for use in humans or animals.

References

Errante, F., Ledwoń, P., Latajka, R., Rovero, P., & Papini, A. M. (2020). https://pmc.ncbi.nlm.nih.gov/articles/PMC4508379/

Gorski, J., Prokopowicz, M., & Mielniczuk, M. (2020). https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/

Maquart, F. X., Pickart, L., Laurent, M., Gillery, P., Monboisse, J. C., & Borel, J. P. (1988). https://pubmed.ncbi.nlm.nih.gov/3169264/

Pickart, L., & Margolina, A. (2018). https://pmc.ncbi.nlm.nih.gov/articles/PMC3359723/

Additional information

Size

100mg/vial

What are peptides?

Peptides are short chains of amino acids that act as signalling molecules in the body, playing a role in a wide range of biological processes including tissue repair, immune response, and cellular communication.

How are peptides used in research?

In research settings, peptides are studied for their ability to interact with specific receptors and biological pathways. This makes them valuable tools for scientific and laboratory analysis, helping researchers better understand how the body functions at a cellular level.

What payment methods do you accept?

We currently accept Credit Card, SEPA bank transfer, iDeal, Google Pay, Apple Pay, and Cryptocurrency (Bitcoin, Ethereum, and USDT).

How should I store my peptides?

All peptides are supplied in lyophilised (freeze-dried) form, ensuring stability during shipping and long-term storage. Unreconstituted vials should be kept in a cool, dry place away from direct light, with refrigeration recommended for extended periods. Once reconstituted for research purposes, peptides should be kept refrigerated and handled using sterile laboratory practices to maintain integrity throughout use.

How does shipping and delivery work?

Orders are processed and dispatched within 48 hours of purchase. Delivery typically takes 6-9 business days depending on your location. Tracking information is available directly on our website. Free shipping is applied automatically on all orders over 150 euros.

Do you offer refunds or returns?

Due to the nature of research products, we are unable to accept returns. However if your order arrives damaged or incorrect please contact us within 48 hours.

How can I be sure of product quality?

All our products are lab-tested by Janoshik to ensure high purity and compliance with research-grade quality standards.

GHK-Cu (Copper Peptide)

GHK-Cu is a naturally occurring tripeptide — glycyl-L-histidyl-L-lysine — complexed with copper(II). First isolated from human plasma albumin in 1973, it is found naturally in plasma, saliva, and wound fluid, but its concentrations decline significantly with age. It has since become one of the most extensively studied peptides in tissue repair and regenerative research (Pickart & Margolina, 2018).

Mechanism of Action

  • GHK-Cu works by attracting immune and repair cells to sites of tissue damage, stimulating fibroblasts — the cells responsible for building and maintaining connective tissue — to produce collagen, elastin, and structural proteins that form the scaffolding of healthy tissue (Maquart et al., 1988)
  • It simultaneously regulates enzymes that break down old or damaged tissue while activating inhibitors of those same enzymes, allowing for controlled and balanced tissue remodelling (Pickart & Margolina, 2018)
  • The copper component activates key enzymes involved in antioxidant defence, blood vessel formation, and connective tissue integrity (Errante et al., 2020)

Key Research Findings

  • Collagen synthesis in cultured fibroblasts was shown to increase significantly with GHK-Cu at concentrations as low as 10⁻¹² mol/L, maximising at 10⁻⁹ mol/L — demonstrating potent biological activity at very small amounts (Maquart et al., 1988)
  • Gene expression analysis revealed GHK-Cu modulates a broad range of biological pathways, with documented effects on wound healing genes, antioxidant responses, anti-inflammatory signalling, and DNA repair processes (Pickart & Margolina, 2018)
  • Preclinical wound models demonstrated accelerated healing of diabetic and ischemic wounds, with reduced inflammatory markers and increased collagen deposition compared to controls (Gorski et al., 2020)

For research use only. Not intended for use in humans or animals.

References

Errante, F., Ledwoń, P., Latajka, R., Rovero, P., & Papini, A. M. (2020). https://pmc.ncbi.nlm.nih.gov/articles/PMC4508379/

Gorski, J., Prokopowicz, M., & Mielniczuk, M. (2020). https://pmc.ncbi.nlm.nih.gov/articles/PMC6073405/

Maquart, F. X., Pickart, L., Laurent, M., Gillery, P., Monboisse, J. C., & Borel, J. P. (1988). https://pubmed.ncbi.nlm.nih.gov/3169264/

Pickart, L., & Margolina, A. (2018). https://pmc.ncbi.nlm.nih.gov/articles/PMC3359723/

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