Tesamorelin

Tesamorelin

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£88.00

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Kit (10 Vials)
Research Use Only: These products are intended for laboratory research purposes only. By purchasing, you confirm you are a qualified researcher and understand this product is not for personal use.
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SKU: TSM10 Category:

Description

Tesamorelin is a modified version of GHRH — the brain’s own signal that tells the pituitary gland to release growth hormone. The modification makes it resistant to the enzyme that normally breaks GHRH down quickly in the bloodstream, giving it a longer window of activity. Because it works by stimulating the body’s own growth hormone production rather than supplying GH directly, it preserves the natural feedback systems that regulate GH levels.

What the research has found

• Clinical trials in subjects with HIV-associated fat redistribution showed tesamorelin produced significant and measurable reductions in visceral (abdominal) fat volume as measured by CT scan, along with improvements in lipid profiles, compared to placebo over 26–52 week periods (Falutz et al., 2010)

• Mechanistic research confirmed these fat-reducing effects work through GH-stimulated lipolysis — the direct breakdown of fat stored in adipose tissue — rather than water loss or redistribution, with corresponding increases in free fatty acid release from fat cells (Stanley et al., 2014)

• A key finding in pharmacokinetic studies was that tesamorelin’s N-terminal chemical modification extends its half-life from approximately 7 minutes (for natural GHRH) to approximately 30 minutes — a substantial improvement that underpins its research utility as a stable GHRH analogue (Stanley et al., 2014)

• Because tesamorelin acts upstream at the pituitary rather than delivering GH directly, studies confirmed it maintains the body’s natural GH feedback loop — an important distinction from direct GH administration in research models (Stanley et al., 2014)

For research use only. Not intended for use in humans or animals.

References
Falutz, J., et al. (2010). https://pubmed.ncbi.nlm.nih.gov/20393159/
Stanley, T. L., & Grinspoon, S. K. (2014). https://pubmed.ncbi.nlm.nih.gov/24423315/

Additional information

Size

10mg/vial

What are peptides?

Peptides are short chains of amino acids that act as signalling molecules in the body, playing a role in a wide range of biological processes including tissue repair, immune response, and cellular communication.

How are peptides used in research?

In research settings, peptides are studied for their ability to interact with specific receptors and biological pathways. This makes them valuable tools for scientific and laboratory analysis, helping researchers better understand how the body functions at a cellular level.

What payment methods do you accept?

We currently accept Credit Card, SEPA bank transfer, iDeal, Google Pay, Apple Pay, and Cryptocurrency (Bitcoin, Ethereum, and USDT).

How should I store my peptides?

All peptides are supplied in lyophilised (freeze-dried) form, ensuring stability during shipping and long-term storage. Unreconstituted vials should be kept in a cool, dry place away from direct light, with refrigeration recommended for extended periods. Once reconstituted for research purposes, peptides should be kept refrigerated and handled using sterile laboratory practices to maintain integrity throughout use.

How does shipping and delivery work?

Orders are processed and dispatched within 48 hours of purchase. Delivery typically takes 6-9 business days depending on your location. Tracking information is available directly on our website. Free shipping is applied automatically on all orders over 150 euros.

Do you offer refunds or returns?

Due to the nature of research products, we are unable to accept returns. However if your order arrives damaged or incorrect please contact us within 48 hours.

How can I be sure of product quality?

All our products are lab-tested by Janoshik to ensure high purity and compliance with research-grade quality standards.

Tesamorelin is a modified version of GHRH — the brain’s own signal that tells the pituitary gland to release growth hormone. The modification makes it resistant to the enzyme that normally breaks GHRH down quickly in the bloodstream, giving it a longer window of activity. Because it works by stimulating the body’s own growth hormone production rather than supplying GH directly, it preserves the natural feedback systems that regulate GH levels.

What the research has found

• Clinical trials in subjects with HIV-associated fat redistribution showed tesamorelin produced significant and measurable reductions in visceral (abdominal) fat volume as measured by CT scan, along with improvements in lipid profiles, compared to placebo over 26–52 week periods (Falutz et al., 2010)

• Mechanistic research confirmed these fat-reducing effects work through GH-stimulated lipolysis — the direct breakdown of fat stored in adipose tissue — rather than water loss or redistribution, with corresponding increases in free fatty acid release from fat cells (Stanley et al., 2014)

• A key finding in pharmacokinetic studies was that tesamorelin’s N-terminal chemical modification extends its half-life from approximately 7 minutes (for natural GHRH) to approximately 30 minutes — a substantial improvement that underpins its research utility as a stable GHRH analogue (Stanley et al., 2014)

• Because tesamorelin acts upstream at the pituitary rather than delivering GH directly, studies confirmed it maintains the body’s natural GH feedback loop — an important distinction from direct GH administration in research models (Stanley et al., 2014)

For research use only. Not intended for use in humans or animals.

References
Falutz, J., et al. (2010). https://pubmed.ncbi.nlm.nih.gov/20393159/
Stanley, T. L., & Grinspoon, S. K. (2014). https://pubmed.ncbi.nlm.nih.gov/24423315/

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